This lesson is the 1st in a unit on constructing Phylogenetic Trees from DNA or Protein Sequences. Students build an Excel spreadsheet to model the simplest implementation of the LCS (Longest Common Subsequence) algorithm in order to calculate the degree of homology between 2 sequences. Read more about Phylogenetic Trees, Part 1: Pairwise Alignment of Related DNA / Protein Sequences using the LCS Algorithm
2.2 Computation and Estimation
Astrobiologists are interested in the salt-loving Archaen, Halobacterium sp. Read more about Could Extraterrestrial Life Look Like An Extremophile?
Bacteria are prokaryotic organisms that can be found almost anywhere on earth. Identifying prokaryotic species can be difficult in a high school lab. The purpose of this lab it to use information that is known about bacteria cell wall composition, size, shape, arrangements, enzymatic activity, colony growth, and molecular data (DNA) to identify species (or group of prokaryotes) of known and Read more about Inquiry Lab: Identifying Bacteria using Morphology, Physiology, and Molecular Data
Online activities, videos, and hands-on labs allow students to visualize and practice bioengineering techniques and concepts in this week-long unit. Students will learn about DNA extraction, restriction enzymes, gel electrophoresis, PCR, and DNA sequencing by answering a series of questions based on videos, diagrams, and prior knowledge. Read more about A Student-Centered Guide to Bioengineering
Dogs and genetics meet in two case studies that encourage students to be detectives. In the first case study, students will use a pedigree to solve a problem about a genetic disorder in a specific dog breed. In the second case study, students will use maps, graphs, and DNA sequencing to determine what animal “meat” is being used in two different brands of dog food. Read more about Canine Case Studies: Using Pedigrees and DNA Sequencing to Solve Problems