How can we identify genes associated with human genetic disorders using online biological databases? Students will be given the nucleotide sequence that links with a human genetic disorder. Read more about Researching Genetic Disorders Using BLAST
3.6B Apply knowledge of information technologies of encoding, transmitting, receiving, storing, retrieving and decoding.
What determines eye color? After learning about different models of how eye color is determined, students will examine phenotypes from 16 subjects and predict if they have B (blue) or non-blue HERC2 gene. Next they will analyze PCR light cycler data and see if that matches their predictions. Read more about Eye Color: Is Blue Really Blue?
In order to better understand DNA fingerprinting and its real world applications, students will use a real genomic site, DNA Surveillance, based in New Zealand, to test whale samples against a standard database. This is done to monitor the sale of protected whale species in Japanese fish markets. Read more about DNA Surveillance Unit: Is That an Endangered Whale You’re Eating?
Students will become familiar with proteomic databases and how they can be used to determine the identity of an unknown protein using laboratory data files created from yeast proteins. Read more about Proteomics: Protein Identification Using On-Line Databases
Students will write a Java program to read a DNA sequence from either the keyboard or a text file. Then they will display the protein sequence that is produced. Students will simulate the mutation of a single location in the DNA sequence to determine the effects of that mutation. Finally, students will look for the locations of a specific DNA sequence. Read more about Decoding a DNA Sequence with Java
Students will write a Microsoft Basic computer program that can be used to determine the possible blood types a child could have based on their parents blood types. Read more about Genetic Blood Types
This lesson is designed to give a student in an introductory computer programming course an interesting, real-life application problem involving string manipulation and DNA sequencing. The programming assignment should be given after students had already been introduced to and required to use a variety of string functions. Read more about Bioinformatics in an Introductory Computer Programming Course
Students will write a Java program that will identify legal donor / recipient pairs based on the mRNA sequence of 6 individuals. Read more about Java Arrays and Blood Donors
Students will complete a Java OOP program that consists of six classes which represent a Gene, a Transcript, and Dictionaries. The Dictionary classes can be used for DNA to RNA transcription and RNA to Protein translation. The Transcript class will contain methods to transcript a DNA coding sequence into an mRNA sequence and to translate an mRNA sequence into a protein. Read more about Process Coding Sequences of Transcripts Lab
Have your students work with String methods in this real world application of the Human Genome for DNA sequencings. Read more about Using the Human Genome to Work with String Methods