Have your students work with String methods in this real world application of the Human Genome for DNA sequencings. Read more about Using the Human Genome to Work with String Methods
This is a simple introductory activity that will allow students to expose themselves to the uses of DNA manipulation in genetic engineering. Students will also practice their reading and writing skills with this activity. They will read, summarize, and form opinions before the curriculum explores how it is done. Read more about Genetic Engineering Introduction
Astrobiologists are interested in the salt-loving Archaen, Halobacterium sp. Read more about Could Extraterrestrial Life Look Like An Extremophile?
This activity will be used to introduce the students to the proper use of pipettes, loading of dyes and reading of electrophoresis gels. This activity could be used as a paper activity without the gel lab if need be. Read more about Practice Gel Electophoresis Activity: Duchenne Muscular Dystrophy
In this case study activity, students read about a disease in the Mennonite population and learn more about the disorder using OMIM. Students will also be introduced to SNP analysis to visualize how the gene that is causing a disorder is found. Students will also get the opportunity to see how mutations can be determined and the effect of these mutations. Read more about Medical Problem Solving using OMIM
This activity is meant to be a self-guided explanation of the endosymbiotic theory with emphasis on mtDNA. It is linked to an assignment where students will BLAST a mtDNA sequence to solve a problem of identity. Read more about Endosymbiotic Theory and mtDNA
A daughter thinks she’s adopted and wants to determine if her parents are her biological parents. Students discover how gel electrophoresis is used to help the daughter determine if she is adopted or not. In addition, students apply previously learned material (pedigree, Punnett square, etc.) to help understand the process and content. Read more about Determining Relationships in Families using Gel Electrophoresis
This activity is designed to explore a real-world application of mtDNA sequencing and analysis. Because mtDNA is very well conserved and is inherited from a mother to her children, cases of unknown identity can be proven. Read more about A Tsar is Born
Students will use their understanding of Mendelian genetics and real-time PCR assays to determine the parental identity for each of the mixed up babies. Read more about A Mix-Up in the Nursery
Is it a case of food poisoning? Your students will have to figure out the cause of a man's illness. After reading a mini case study, students will analyze the remains of the sub sandwhich to determine if there are prokaryotic organisms that caused the illness. Students will use PCR analysis and gel electrophoresis. Read more about What Was In That Sandwich?