Grade 10

Molecular Sequences & Primate Evolution: An Amino Acid Example

In this activity students will used macromolecular data to construct a cladogram of 7 primate species and 1 non-primate species.  This will convey to students the idea that monophyleticism in both the recent and the more distant past can be inferred from macromolecular data. Students will compare and analyze amino acid sequences using NCBI’s BLAST tool. Read more about Molecular Sequences & Primate Evolution: An Amino Acid Example

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Teaching Bioinformatics Using Journals

Teaching Bioinformatics Using Journals is an acivity designed to help students learn the real world applications of bioinformatics and current research in genomics.  It also gives students the opportunity to learn how to read a scientific journal.  After completing this activity students will have several strategies to read and better understand a scientific journal. Read more about Teaching Bioinformatics Using Journals

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A Student-Centered Guide to Bioengineering

Online activities, videos, and hands-on labs allow students to visualize and practice bioengineering techniques and concepts in this week-long unit.  Students will learn about DNA extraction, restriction enzymes, gel electrophoresis, PCR, and DNA sequencing by answering a series of questions based on videos, diagrams, and prior knowledge. Read more about A Student-Centered Guide to Bioengineering

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Canine Case Studies: Using Pedigrees and DNA Sequencing to Solve Problems

Dogs and genetics meet in two case studies that encourage students to be detectives.  In the first case study, students will use a pedigree to solve a problem about a genetic disorder in a specific dog breed.  In the second case study, students will use maps, graphs, and DNA sequencing to determine what animal “meat” is being used in two different brands of dog food.   Read more about Canine Case Studies: Using Pedigrees and DNA Sequencing to Solve Problems

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Bacteria Primer Comparison 2: Gel Electrophoresis

This lesson will occur after a lesson in which the students will isolate bacterial DNA by using primers and PCR. In this lesson, each student will be able to accept or reject his or her hypothesis by completing gel electrophoresis of the PCR product and analyzing the results compared to the other bacterial primer products and a ladder.   Read more about Bacteria Primer Comparison 2: Gel Electrophoresis

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Bacteria Primer Comparison 1: PCR

This lesson will allow students to become familiar with the PCR process by using the thermocycler after discussing the process and its purpose along with completing an online simulation of it.  It will also allow the students to hypothesize which primer will work best with the various prokaryotic samples and then analyze their results after researching basic characteristics about the bacteria Read more about Bacteria Primer Comparison 1: PCR

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Blue People of Kentucky

In this activity students will be introduced to an unusual and rare genetic condition that causes a person's skin to turn blue.   A powerpoint presentation will be used to introduce the topic.  The presentation will open up opportunities to review genetic concepts as well as create discussion on topics like population genetics, ethics, etc.  Students will examine a pedigree where they will see Read more about Blue People of Kentucky

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In the Year 2525… Using Real Time PCR Data to Analyze a Founder Scenario

This activity will place the concepts of Hardy-Weinberg equilibrium into a contemporary context.  During the activity students will interpret data from real-time PCR and use it to calculate allele frequencies.  These allele frequencies will then serve as a hypothetical founder population, for which students will run simulations using Allele A1 software to predict possible future allele frequen Read more about In the Year 2525… Using Real Time PCR Data to Analyze a Founder Scenario

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