How can we identify genes associated with human genetic disorders using online biological databases? Students will be given the nucleotide sequence that links with a human genetic disorder. Read more about Researching Genetic Disorders Using BLAST
This lesson is a research activity on genetic disorders. It emphasizes the use of Online Inheritance of Man (OMIM), as well as other genetic databases. The student will locate the gene or genes involved with a disorder, discuss symptoms, prevalence, and possible treatment and present this material to the class using Prezi (presentation tool). Read more about Genetic Disorder Research
This is an introductory lesson on cloning. It is a mini webquest that gives students an opportunity to learn about the different ways clones come about and then gives them the opportunity to participate in a somatic cell nuclear transfer in a virtual mouse. Through this lesson, students will develop an understanding of cloning and the different techniques used to accomplish it. After this l Read more about What is Cloning?
This is an introductory lesson to DNA. It involves an activity that gives students an opportunity to examine real human DNA they extract from the inside of their mouths. Through this engaging activity, students will develop an understanding of DNA as a real, tangible substance. Students will take notice of how their observations from the investigation are different or consistent with thei Read more about DNA Detectives: Extract your Own DNA
In order to better understand DNA fingerprinting and its real world applications, students will use a real genomic site, DNA Surveillance, based in New Zealand, to test whale samples against a standard database. This is done to monitor the sale of protected whale species in Japanese fish markets. Read more about DNA Surveillance Unit: Is That an Endangered Whale You’re Eating?
This lesson is the 1st in a unit on constructing Phylogenetic Trees from DNA or Protein Sequences. Students build an Excel spreadsheet to model the simplest implementation of the LCS (Longest Common Subsequence) algorithm in order to calculate the degree of homology between 2 sequences. Read more about Phylogenetic Trees, Part 1: Pairwise Alignment of Related DNA / Protein Sequences using the LCS Algorithm
This activity will familiarize high school students on the importance of computational biology in today's world. By writing computer programs that use genomics sequence analysis, the student will have a better understanding of molecular biology and how the vast amount of data that is provided in multiple on-line databases can be simplified by a few lines of code. Read more about Bioinformatics Using Basic Genomics Sequences
This lesson is designed to give a student in an introductory computer programming course an interesting, real-life application problem involving string manipulation and DNA sequencing. The programming assignment should be given after students had already been introduced to and required to use a variety of string functions. Read more about Bioinformatics in an Introductory Computer Programming Course
Students will write a Visual BASIC computer program that first asks the user to enter the phenotype and then the genotype of the parents. The program will then use that information to predict the blood type of the children. Read more about Visual BASIC Blood Type Predictor
Students will complete a Java OOP program that consists of six classes which represent a Gene, a Transcript, and Dictionaries. The Dictionary classes can be used for DNA to RNA transcription and RNA to Protein translation. The Transcript class will contain methods to transcript a DNA coding sequence into an mRNA sequence and to translate an mRNA sequence into a protein. Read more about Process Coding Sequences of Transcripts Lab