DNA

DNA Detectives: Extract your Own DNA

This is an introductory lesson to DNA.  It involves an activity that gives students an opportunity to examine real human DNA they extract from the inside of their mouths.  Through this engaging activity, students will develop an  understanding of DNA as a real, tangible substance.   Students will take notice of how their observations from the investigation are different or consistent with thei Read more about DNA Detectives: Extract your Own DNA

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Detecting a Transposon Tag in Arabidopsis

This lab - produced by the DNA Learning Center and available at http://www.greenomes.org/ - allows students to investigate a gene in Arabidopsis to analyze the molecular relationship between genotyes and phenotypes.  It also helps them understand the use of transposable elements to mutagenize and tag genes as well as the role of homeotic genes i Read more about Detecting a Transposon Tag in Arabidopsis

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Process Coding Sequences of Transcripts Lab

Students will complete a Java OOP program that consists of six classes which represent a Gene, a Transcript, and Dictionaries. The Dictionary classes can be used for DNA to RNA transcription and RNA to Protein translation. The Transcript class will contain methods to transcript a DNA coding sequence into an mRNA sequence and to translate an mRNA sequence into a protein. Read more about Process Coding Sequences of Transcripts Lab

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A Progression of Computer Science Problems with Bioinformatics as the Context

This activity, a question set for teaching basic computer science ideas via bioinformatics, provides a variety of problems that build on students abilities in both computer science and bioinformatics. The questions get progressively more difficult and build off previous problems although any could be used as a stand alone as well.  Read more about A Progression of Computer Science Problems with Bioinformatics as the Context

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Bacteria Primer Comparison 2: Gel Electrophoresis

This lesson will occur after a lesson in which the students will isolate bacterial DNA by using primers and PCR. In this lesson, each student will be able to accept or reject his or her hypothesis by completing gel electrophoresis of the PCR product and analyzing the results compared to the other bacterial primer products and a ladder.   Read more about Bacteria Primer Comparison 2: Gel Electrophoresis

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Molecular Conservation & Evolutionary Relationships

Students attempt to determine how sequences are used as evolutionary tools to determine relative age of relationship of organisms. Students are given sections of DNA and amino acid sequences and asked to determine differences between them. In part 1, students work with online DNA sequences found on BLAST. In part 2, students use paper based amino acid sequences. Read more about Molecular Conservation & Evolutionary Relationships

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