genetics

Eye Color: Is Blue Really Blue?

What determines eye color? After learning about different models of how eye color is determined, students will examine phenotypes from 16 subjects and predict if they have B (blue) or non-blue HERC2 gene. Next they will analyze PCR light cycler data and see if that matches their predictions. Read more about Eye Color: Is Blue Really Blue?

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Detecting a Transposon Tag in Arabidopsis

This lab - produced by the DNA Learning Center and available at http://www.greenomes.org/ - allows students to investigate a gene in Arabidopsis to analyze the molecular relationship between genotyes and phenotypes.  It also helps them understand the use of transposable elements to mutagenize and tag genes as well as the role of homeotic genes i Read more about Detecting a Transposon Tag in Arabidopsis

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Process Coding Sequences of Transcripts Lab

Students will complete a Java OOP program that consists of six classes which represent a Gene, a Transcript, and Dictionaries. The Dictionary classes can be used for DNA to RNA transcription and RNA to Protein translation. The Transcript class will contain methods to transcript a DNA coding sequence into an mRNA sequence and to translate an mRNA sequence into a protein. Read more about Process Coding Sequences of Transcripts Lab

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Medical Problem Solving using OMIM

In this case study activity, students read about a disease in the Mennonite population and learn more about the disorder using OMIM.  Students will also be introduced to SNP analysis to visualize how the gene that is causing a disorder is found.  Students will also get the opportunity to see how mutations can be determined and the effect of these mutations. Read more about Medical Problem Solving using OMIM

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Determining Relationships in Families using Gel Electrophoresis

A daughter thinks she’s adopted and wants to determine if her parents are her biological parents.  Students discover how gel electrophoresis is used to help the daughter determine if she is adopted or not.  In addition, students apply previously learned material (pedigree, Punnett square, etc.) to help understand the process and content.  Read more about Determining Relationships in Families using Gel Electrophoresis

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Blue People of Kentucky

In this activity students will be introduced to an unusual and rare genetic condition that causes a person's skin to turn blue.   A powerpoint presentation will be used to introduce the topic.  The presentation will open up opportunities to review genetic concepts as well as create discussion on topics like population genetics, ethics, etc.  Students will examine a pedigree where they will see Read more about Blue People of Kentucky

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As easy as one, two, pee: A study of Alkaptonuria

This lesson introduces students to the Orina family.  Carlos, a member of the Orina family, has been diagnosed with a genetic disease called Alkaptonuria, which makes a person's urine turn dark black.  During this lesson, students first take on the role of a geneticist and use the OMIM database to prepare a one-page summary sheet that could be presented to the Orina family with information abo Read more about As easy as one, two, pee: A study of Alkaptonuria

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