Students will complete a Java OOP program that consists of six classes which represent a Gene, a Transcript, and Dictionaries. The Dictionary classes can be used for DNA to RNA transcription and RNA to Protein translation. The Transcript class will contain methods to transcript a DNA coding sequence into an mRNA sequence and to translate an mRNA sequence into a protein. Read more about Process Coding Sequences of Transcripts Lab
In this activity students will used macromolecular data to construct a cladogram of 7 primate species and 1 non-primate species. This will convey to students the idea that monophyleticism in both the recent and the more distant past can be inferred from macromolecular data. Students will compare and analyze amino acid sequences using NCBI’s BLAST tool. Read more about Molecular Sequences & Primate Evolution: An Amino Acid Example
What connections exist between proteins and genes and figuring out evolutionary relationships? Students will use SDS-PAGE to analyze different fish proteins. Analysis of proteins will be used to predict evolutionary relationships among different fish. Read more about Fish Evolution
What is the structure and function of the nervous system? How do you use bioinformatics relational databases to explore biological molecules? Students will explore the Genes 2 Cognition website and then chose a particular molecule to investigate further. Students will use a variety of resources, including OMIM, NCBI, Allen Brain Atlas, Ensemble, and Entrez.
Read more about Exploring the Neuroscience of the Human Brain Using Bioinformatics
Students attempt to determine how sequences are used as evolutionary tools to determine relative age of relationship of organisms. Students are given sections of DNA and amino acid sequences and asked to determine differences between them. In part 1, students work with online DNA sequences found on BLAST. In part 2, students use paper based amino acid sequences. Read more about Molecular Conservation & Evolutionary Relationships
Students will write a Visual Basic computer program that can be used to transcribe a DNA codon into
mRNA and then translate the mRNA sequence into the correct amino acid. Read more about Visual Basic DNA Decoder