How can we identify genes associated with human genetic disorders using online biological databases? Students will be given the nucleotide sequence that links with a human genetic disorder. Read more about Researching Genetic Disorders Using BLAST
DNA, RNA, Genetics and Genomics
Bioinformatics-based lessons are a powerful way to guide students to a deep and comprehensive study of genetics. The lessons in our collection span all levels of biology, from “seeing” DNA, to using gene sequences to identify and learn about genetic diseases, to analyzing PCR data in order to answer complex questions.
The webquest uses the same story and data as Case 1, but differs in approach. Students take on the roles of a doctor and a geneticist at The Clinic for Special Children. Together, they follow the steps of the webquest to diagnose and treat a young boy. Read more about Medical Problem Solving Webquest
What determines eye color? After learning about different models of how eye color is determined, students will examine phenotypes from 16 subjects and predict if they have B (blue) or non-blue HERC2 gene. Next they will analyze PCR light cycler data and see if that matches their predictions. Read more about Eye Color: Is Blue Really Blue?
This lesson is a research activity on genetic disorders. It emphasizes the use of Online Inheritance of Man (OMIM), as well as other genetic databases. The student will locate the gene or genes involved with a disorder, discuss symptoms, prevalence, and possible treatment and present this material to the class using Prezi (presentation tool). Read more about Genetic Disorder Research
This is an introductory lesson on cloning. It is a mini webquest that gives students an opportunity to learn about the different ways clones come about and then gives them the opportunity to participate in a somatic cell nuclear transfer in a virtual mouse. Through this lesson, students will develop an understanding of cloning and the different techniques used to accomplish it. After this l Read more about What is Cloning?
This is an introductory lesson to DNA. It involves an activity that gives students an opportunity to examine real human DNA they extract from the inside of their mouths. Through this engaging activity, students will develop an understanding of DNA as a real, tangible substance. Students will take notice of how their observations from the investigation are different or consistent with thei Read more about DNA Detectives: Extract your Own DNA
This lab - produced by the DNA Learning Center and available at http://www.greenomes.org/ - allows students to investigate a gene in Arabidopsis to analyze the molecular relationship between genotyes and phenotypes. It also helps them understand the use of transposable elements to mutagenize and tag genes as well as the role of homeotic genes i Read more about Detecting a Transposon Tag in Arabidopsis
Have your students work with String methods in this real world application of the Human Genome for DNA sequencings. Read more about Using the Human Genome to Work with String Methods
This is a simple introductory activity that will allow students to expose themselves to the uses of DNA manipulation in genetic engineering. Students will also practice their reading and writing skills with this activity. They will read, summarize, and form opinions before the curriculum explores how it is done. Read more about Genetic Engineering Introduction
This activity will be used to introduce the students to the proper use of pipettes, loading of dyes and reading of electrophoresis gels. This activity could be used as a paper activity without the gel lab if need be. Read more about Practice Gel Electophoresis Activity: Duchenne Muscular Dystrophy