Proteins and Proteomics

Proteins are the agents of change within a cell. Because proteins van vary with time or in response to stresses, comparing and understanding the proteins can help us better understand how systems or organisms have changed. To do so, it’s useful to have access to the tools of proteomics, the large-scale study of proteins. Use the lessons below to apply bioinformatics to your students’ investigations about proteins.

Fish Evolution

What connections exist between proteins and genes and figuring out evolutionary relationships? Students will use SDS-PAGE to analyze different fish proteins. Analysis of proteins will be used to predict evolutionary relationships among different fish.    Read more about Fish Evolution

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Exploring the Neuroscience of the Human Brain Using Bioinformatics

What is the structure and function of the nervous system? How do you use bioinformatics relational databases to explore biological molecules?  Students will explore the Genes 2 Cognition website and then chose a particular molecule to investigate further.  Students will use a variety of resources, including OMIM, NCBI, Allen Brain Atlas, Ensemble, and Entrez.
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