Biology

Modes of DNA Analysis: Extraction, Electrophoresis, PCR, and Microarray

Students will develop an understanding of available technologies that assist in analyzing DNA. Students will work virtually though the processes of DNA extraction, PCR, Gel electrophoresis, and DNA microarrays. Virtual extraction and electrophoresis labs will be used to show students the process before they actually do the process themselves. Read more about Modes of DNA Analysis: Extraction, Electrophoresis, PCR, and Microarray

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The Central Dogma of Biology: DNA to Protein

The Central Dogma activity provides students practice in the transcription and translation of a small segment of an actual gene in the human body.  Students then use BLASTn to identify their sequence as well as the program CN3D to view 3-D models of their protein.  The activity concludes with the connection between mutation and disease as students investigate the cond Read more about The Central Dogma of Biology: DNA to Protein

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The Power of Mitochondrial DNA: The Case of the Disappeared Children of Argentina

The Power of Mitochondrial DNA: The Case of the Disappeared Children of Argentina is a real world application of the use of mtDNA to solve a problem.  Students assume the role of scientists who work to determine paternity and maternity relationships in custody battles and incidences of abduction.  Students must help four families try to find lost infants that were given to other families after Read more about The Power of Mitochondrial DNA: The Case of the Disappeared Children of Argentina

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Determining Molecular Genotype from Phenotype: Real Time PCR Analysis

Students will learn about lightcyclers (real time PCR), a biotechnology used to help determine molecular genotype of blood types. They will analyze sample lightcycler outputs to determine blood type and possible molecular genotypes of humans. Read more about Determining Molecular Genotype from Phenotype: Real Time PCR Analysis

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ABO Blood Types with Chi Square Analysis

Students will read and review background information on the ABO blood groups and will practice blood type problems to ensure their understanding of multiple allele genetics.  Students will analyze blood types of the US population, make comparisons, and evaluate the significance using Chi Square analysis. Read more about ABO Blood Types with Chi Square Analysis

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The Importance of Anatomy and Physiology in Understanding Symptoms

Desgined for use early in an Anatomy and Physiology course, this presentation shows students how an understanding of systems interactions is used by medical professionals to diagnosis different disorders. This lesson introduces OMIM, Online Mendelian Inheritance in Man, a database that collects information on diseases and disorders. Read more about The Importance of Anatomy and Physiology in Understanding Symptoms

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Molecular Conservation & Evolutionary Relationships

Students attempt to determine how sequences are used as evolutionary tools to determine relative age of relationship of organisms. Students are given sections of DNA and amino acid sequences and asked to determine differences between them. In part 1, students work with online DNA sequences found on BLAST. In part 2, students use paper based amino acid sequences. Read more about Molecular Conservation & Evolutionary Relationships

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