Computer lab

In the Year 2525… Using Real Time PCR Data to Analyze a Founder Scenario

This activity will place the concepts of Hardy-Weinberg equilibrium into a contemporary context.  During the activity students will interpret data from real-time PCR and use it to calculate allele frequencies.  These allele frequencies will then serve as a hypothetical founder population, for which students will run simulations using Allele A1 software to predict possible future allele frequen Read more about In the Year 2525… Using Real Time PCR Data to Analyze a Founder Scenario

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Exploring the Neuroscience of the Human Brain Using Bioinformatics

What is the structure and function of the nervous system? How do you use bioinformatics relational databases to explore biological molecules?  Students will explore the Genes 2 Cognition website and then chose a particular molecule to investigate further.  Students will use a variety of resources, including OMIM, NCBI, Allen Brain Atlas, Ensemble, and Entrez.
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Modes of DNA Analysis: Extraction, Electrophoresis, PCR, and Microarray

Students will develop an understanding of available technologies that assist in analyzing DNA. Students will work virtually though the processes of DNA extraction, PCR, Gel electrophoresis, and DNA microarrays. Virtual extraction and electrophoresis labs will be used to show students the process before they actually do the process themselves. Read more about Modes of DNA Analysis: Extraction, Electrophoresis, PCR, and Microarray

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The Power of Mitochondrial DNA: The Case of the Disappeared Children of Argentina

The Power of Mitochondrial DNA: The Case of the Disappeared Children of Argentina is a real world application of the use of mtDNA to solve a problem.  Students assume the role of scientists who work to determine paternity and maternity relationships in custody battles and incidences of abduction.  Students must help four families try to find lost infants that were given to other families after Read more about The Power of Mitochondrial DNA: The Case of the Disappeared Children of Argentina

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As easy as one, two, pee: A study of Alkaptonuria

This lesson introduces students to the Orina family.  Carlos, a member of the Orina family, has been diagnosed with a genetic disease called Alkaptonuria, which makes a person's urine turn dark black.  During this lesson, students first take on the role of a geneticist and use the OMIM database to prepare a one-page summary sheet that could be presented to the Orina family with information abo Read more about As easy as one, two, pee: A study of Alkaptonuria

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Molecular Conservation & Evolutionary Relationships

Students attempt to determine how sequences are used as evolutionary tools to determine relative age of relationship of organisms. Students are given sections of DNA and amino acid sequences and asked to determine differences between them. In part 1, students work with online DNA sequences found on BLAST. In part 2, students use paper based amino acid sequences. Read more about Molecular Conservation & Evolutionary Relationships

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