Worksheet

What is Cloning?

This is an introductory lesson on cloning.  It is a mini webquest that gives students an opportunity to learn about the different ways clones come about and then gives them the opportunity to participate in a somatic cell nuclear transfer in a virtual mouse.  Through this lesson, students will develop an understanding of cloning and the different techniques used to accomplish it.  After this l Read more about What is Cloning?

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Investigating Human Genetic Disorders

This activity is designed to provide students with a greater depth of understanding of the causes of human genetic disorders. It will also take  students through an exploration of the processes that can be used by physicians and geneticists on quest for medical diagnoses and treatments by utilizing various online databases. Read more about Investigating Human Genetic Disorders

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Canine Case Studies: Using Pedigrees and DNA Sequencing to Solve Problems

Dogs and genetics meet in two case studies that encourage students to be detectives.  In the first case study, students will use a pedigree to solve a problem about a genetic disorder in a specific dog breed.  In the second case study, students will use maps, graphs, and DNA sequencing to determine what animal “meat” is being used in two different brands of dog food.   Read more about Canine Case Studies: Using Pedigrees and DNA Sequencing to Solve Problems

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In the Year 2525… Using Real Time PCR Data to Analyze a Founder Scenario

This activity will place the concepts of Hardy-Weinberg equilibrium into a contemporary context.  During the activity students will interpret data from real-time PCR and use it to calculate allele frequencies.  These allele frequencies will then serve as a hypothetical founder population, for which students will run simulations using Allele A1 software to predict possible future allele frequen Read more about In the Year 2525… Using Real Time PCR Data to Analyze a Founder Scenario

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Who Dunnit? The Case of the Missing Laptop

The Case of the Missing Laptop is designed to be used as a unit.  It begins with a story about a petty high school crime and some DNA evidence found at the crime scene.  Students are taken through a problem-solving process as they learn techniques that would help them assess the DNA evidence from the crime scene to identify the perpetrator. Read more about Who Dunnit? The Case of the Missing Laptop

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Determining Molecular Genotype from Phenotype: Real Time PCR Analysis

Students will learn about lightcyclers (real time PCR), a biotechnology used to help determine molecular genotype of blood types. They will analyze sample lightcycler outputs to determine blood type and possible molecular genotypes of humans. Read more about Determining Molecular Genotype from Phenotype: Real Time PCR Analysis

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